Chronic Fatigue Syndrome History: An Introduction
Although the cluster of symptoms we know as
chronic fatigue syndrome (CFS) has been described over the years under many names with varying definitions and suspected causes, it was not until 1988 that a formal case definition emerged.
Chronic Fatigue Syndrome History: Epstein-Barr Virus Syndrome
In the early 1980s, patients with symptoms such as fatigue, muscle pain, and
depression were often diagnosed with chronic Epstein-Barr virus (EBV) syndrome or chronic
mononucleosis (mono) syndrome. However, researchers could not isolate EBV as the cause of CFS.
Chronic Fatigue Syndrome History: CFS Emerges
In 1988, in an effort to standardize research definitions, a group of experts led by the Centers for Disease Control and Prevention (CDC) proposed
chronic fatigue syndrome to be the new name for Epstein-Barr virus syndrome.
The new definition entailed:
- Persistent or relapsing, debilitating fatigue, lasting at least six months, in a person who has no previous history of similar symptoms
- Exclusion of other clinical conditions that may produce similar symptoms
- Occurrence of at least eight symptoms, including mild fever, sore throat, painful lymph nodes, prolonged fatigue after exercise, joint or muscle pain, unexplained muscle weakness, headaches, and sleep disturbance.