Glutathione Dosage

Because the safest and most effective dosage of glutathione has not yet been established, it is a good idea to follow the directions on the label of your particular glutathione product. Research indicates that taking glutathione by mouth may not be effective, as this substance is not well absorbed by the body when taken orally. However, typical glutathione dosages (based on some studies that have been done) range from 50 mg to 600 mg.

 

An Introduction to Glutathione Dosage

The best dose of glutathione for most uses has not yet been determined. Because glutathione is a dietary supplement (not a drug) there is little information available to provide guidance about safe and effective glutathione dosages.
 

Reasonable Dosing for Glutathione

When taken by mouth, most glutathione dosages range from 50 mg to 600 mg. However, it should be noted that research suggests that glutathione is not significantly absorbed into the body when taken by mouth (so it is likely that no dose of glutathione taken by mouth is effective). When inhaled, a dose of 600 mg twice daily has been recommended. When given as an intramuscular injection, a dose of 600 mg every day or every other day has been suggested by some clinical studies. A few studies that have used glutathione intravenously (IV) have used doses based on body surface area (a measure calculated using your height and weight).
 
The best dosage of glutathione has not been clearly established for any use. It is reasonable to follow the directions on the label of your particular glutathione product. Do not exceed these recommendations unless your healthcare provider specifically instructs you to do so.
 

General Glutathione Dosage Information

Some considerations for people taking glutathione include:
 
  • Because the manufacturing of dietary supplements (such glutathione) is not closely regulated, it is important to choose a trustworthy manufacturer for glutathione supplements. It is a good idea to look for the "USP" symbol, as this means that the supplement has been tested and contains the right ingredients in the right amounts. For glutathione that is inhaled or injected, it is important to choose a competent and qualified pharmacy to make such products (as they are not available commercially).
     
  • Glutathione is popular among practitioners of complementary and alternative medicine. As should be done with all healthcare providers, it is important to choose a complementary or alternative medicine practitioner who is qualified and reputable.
     
  • If you have any chronic health problems or take any prescription medications, it is probably a good idea to check with your healthcare provider before taking glutathione.
     
  • If you are unsure about anything related to your dosage or glutathione dosing in general, please talk with your healthcare provider.
     
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;