Glutathione Drug Interactions

Acetaminophen and alcohol can negatively interact with glutathione. Drug interactions with glutathione may counteract the benefits of glutathione, decreasing its ability to detoxify certain chemicals in the body. To avoid this complication, you should talk to your healthcare provider about the possible interactions that may apply to you.

 

An Introduction to Glutathione Drug Interactions

Even though it is a dietary supplement (not a "drug"), glutathione can potentially interact with a few substances. Some of the substances that may lead to glutathione interactions include:
 
 

Interactions With Glutathione Explained

The following sections explain in detail the potentially negative interactions that can occur when glutathione is combined with any of the substances listed above.
 
Acetaminophen
The body uses glutathione to detoxify a toxic metabolite of acetaminophen. Glutathione is "used up" in the chemical reaction, and it is possible that taking acetaminophen (especially in large doses) could counteract the benefits of glutathione.
 
Alcohol
A chronic use of alcohol depletes the body's glutathione and could potentially counteract the benefits of glutathione.
 

Final Thoughts on Glutathione Drug Interactions

It is possible that not every drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the glutathione interactions that may apply to you.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;